A clinical trial supported by the National Institute on Drug Abuse (NIDA) marks the first successful, placebo-controlled demonstration of a vaccine against illicit drug addiction. The anti-cocaine vaccine causes the immune system to produces antibodies that attach to cocaine molecules, preventing them from entering the brain. Thus, the vaccine blocks the drug’s effect.   The...

Many studies present evidence that antisocial personality disorder (ASPD) is highly associated with substance use disorders (SUD). The DSM-IV defines ASPD as “a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood.” Characteristics of individuals with ASPD may include persistent lying...

Using drugs during pregnancy creates multiple risks for the mother as well as the baby. Drug use during pregnancy may lead to miscarriage or severe developmental abnormalities for the child. Yet little research has examined the motivation for drug treatment among pregnant women. Researchers at Johns Hopkins University hypothesized that pregnant drug-using women would be more...

Although drug courts successfully reduce rates of recidivism for participants, research indicates that there is a need to develop mental health screenings to detect co-occurring mental health issues during associated drug treatment.   What is a Drug Court? Drug courts are specialized court dockets that bring together judiciary, prosecution, defense, probation, law enforcement, mental health...

Inpatient or residential drug rehab programs can be stressful for residents on several different levels. Residents may experience stress as a symptom of withdrawal. Some treatment sessions will likely activate emotions and trigger stress. For many patients, pre-existing stress played a major role in the development of their addiction. An effective approach to stress management...

Pharmacogenetics looks at genetic variation to predict individual differences in response to medications. Individuals may metabolize the same medication in different ways, and their genotype may indicate some of these differences in drug metabolism. Proponents of pharmacogenetics hope that this relatively new field of study will lead to increased efficacy and safety for a wide...

Methamphetamine use has been linked to increased risk of human immunodeficiency virus (HIV) among gay men. Methamphetamine is a highly addictive stimulant that may lower inhibitions, increase sexual arousal, and lead to risky sexual behavior such as unprotected sex. Further, methamphetamine may be injected, and needle-sharing is also a risk factor for HIV.  These two...

Cluster B personality disorders (e.g., borderline personality disorder) and substance use disorders (SUD) are both marked by impulsivity and poor behavioral control. Previous studies (e.g., Taylor, 2005) have found evidence that symptoms of cluster B personality disorder and SUD are significantly and positively correlated. Because of accumulating evidence which suggests that personality disorders are prevalent...